We had this issue a few days ago, it's already solved but someone might find it useful to solve the same problem:
Issue: Simulator doesn't work on OD (any version), with a fresh install of the latest windows 10 or a recently upgraded copy.
If you go to to the error log will see something like :
java.lang.UnsatisfiedLinkError: C:\lib\eclipse\plugins\com.avaya.sceavb_188.8.131.521\AVBControl64.dll: Can't find dependent libraries
at java.lang.ClassLoader$NativeLibrary.load(Native Method)
at java.lang.ClassLoader.loadLibrary0(Unknown Source)
at java.lang.ClassLoader.loadLibrary(Unknown Source)
Solution: last version of windows changed /c/WINDOWS/SYSTEM32/MSVCR100.dll --> MSVCR130.dll so OD is not able to find it. Just copy or download the MSVCR100.dll library into your SYSTEM32 folder.
I don't know if future OD versions or patches will address this issue, but this workaround works.